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Tocris Bioscience™ Guangxitoxin 1E
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Catalog No. 5676100U
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Quantity:
100 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent Kv2.1 and Kv2.2 channel blocker

Guangxitoxin 1E is a Kv2.1 and Kv2.2 channel blocker (IC50 values are 1-3 nM). Enhances glucose-stimulated insulin secretion from human islets in vitro, but not from islet cells lacking the Kv2.1 channel. Has no significant effect on plasma insulin, glucagon or blood glucose levels in mice, but increases plasma somatostatin levels.

Specifications

CAS 1233152-82-3
Content And Storage Store at -20°C
Description Voltage-gated Potassium Channel Blockers
Molecular Weight (g/mol) Observed M.W.: 3948.61
Quantity 100 μg
Structural Form C178H248N44O45S7
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