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Thermo Scientific Chemicals Guanidine thiocyanate, Molecular Biology Grade
Description
Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins.
Solubility
Soluble in water (1420 g/L) at 20°C, and ethanol (5%).
Notes
Light Sensitive. Keep container tightly closed. Store away from oxidizing agents.
Specifications
Specifications
| Melting Point | 118°C to 122°C |
| Color | White |
| Density | 1.29 |
| Quantity | 50 g |
| Beilstein | 3563461 |
| Sensitivity | Light sensitive |
| Solubility Information | Soluble in water (1420g/L) at 20°C,and ethanol (5%). |
| Formula Weight | 118.16 |
| Grade | Molecular Biology |
| Physical Form | Powder |
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Safety and Handling
| Hazard Category | Skin corrosion/irritation (category 1), Hazardous to the aquatic environment (chronic category 3), Acute toxicity (category 4) |
| Hazard Statement | Corrosive to the respiratory tract, Causes severe skin burns and eye damage, Contact with acids liberates very toxic gas, Harmful to aquatic life with long lasting effects, Harmful if swallowed, in contact with skin or if inhaled |
| DOTInformation | Hazard Class: 8; Packaging Group: III |
| EINECSNumber | 209-812-1 |
| RTECSNumber | XL1225000 |
| TSCA | Yes |
| Recommended Storage | Ambient temperatures |
RUO – Research Use Only
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