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Cayman Chemical GunosIn 5-dIphosphatesod 5mg
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Supplier:  Cayman Chemical 317045 MG

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A T-type calcium channel blocker inhibits inactivated-state Cav3 2 channels (IC50 2 3 M) and inactivated-state Cav3 1 and Cav3 3 channels by 50 and 39 respectively at 10 M selectively inhibits inactivated-state T-type calcium currents over resting-state currents in rat DRG neurons (IC50s 7 6 and 30 M respectively) reverses the hind limb grip force deficit in a rat model of MIA-induced osteoarthritic pain (ED50 2 mg/kg) dose-dependently increases the paw withdrawal threshold in rat SNL and CCI models of neuropathic pain attenuates cold allodynia in the CCI rat model at 3 mg/kg

Catalog No. 50-299-0701


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