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Invitrogen™ H1FOO Polyclonal Antibody
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Catalog No. PIPA536111
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PIPA536111 100 μL
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Catalog No. PIPA536111 Supplier Invitrogen™ Supplier No. PA536111
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 35 kDa. Purity is >95% by SDS-PAGE.

Eukaryotic Histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fibers. Two molecules of each of the four core Histones (Histone H2A, H2B, H3, and H4) form the octamer, which consists of two H2A-H2B dimers and two H3-H4 dimers that are nearly symmetrical by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. H1FOO (H1 histone family, member O, oocyte-specific), also known as OSH1, is a 346 amino acid oocyte-specific Histone that localizes to both the nucleus and the cytoplasm. Expressed as multiple alternatively spliced isoforms, H1FOO is thought to play an important role in gene control during oogenesis and early embryogenesis and is crucial for meiotic maturation of germinal vesicle-stage oocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen H1FOO
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide; pH 7.2
Gene H1FOO
Gene Accession No. Q8IZA3
Gene Alias C86609; H1 histone family member O, oocyte specific; H1 histone family, member O, oocyte-specific; H1.8; H1fo; H1foo; H1OO; Histone H1oo; oocyte-specific histone H1; Oocyte-specific linker histone H1; OSH1; RGD1566236
Gene Symbols H1FOO
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the N-terminal of human Histone H1oo.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 132243
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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