Genscript Corporation H1N1 A/California/04/2009 H

Supplier:  Genscript Corporation Z0318110

Influenza hemagglutinin (HA) is a glycoprotein found on the surface of the influenzavirus It is responsible for binding the virus to cells with sialic acid on their membranes such as cells in the upper respiratory tract or erythrocytes It is also responsible for the fusion of the viral envelope with the endosome membrane after the pH has been reduced The name hemagglutinin comes from the protein s ability to cause red blood cells (erythrocytes) to clump together in vitro HA has two functions First it allows the recognition of target vertebrate cells accomplished through binding to these cells sialic acid-containing receptors Second once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane H1N1 is a subtype of influenza virus A and the most common cause of influenza in humans

Catalog No. 50-000-59500