H2AFY2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 170301AP150UL
DescriptionVariant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
|Core histone macro H2A.2, H2A histone family, member Y2, H2AFY2, Histone macroH2A2, macroH2A2, mH2A2|
|Antigen Affinity Chromatography|
|361844, 404634, 55506|
|Immunoprecipitation, Western Blot|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|H2AFY2 Fusion Protein Ag10487|
|Human, Mouse, Rat|
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