Invitrogen™ HAND1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597267

Catalog No. PIPA597267

Description

Immunogen sequence: PHPAHPMLHE PFLFGPASRC HQERPYFQSW LLSPADAAPD FPAGGPPPAA AAAATAYGPD ARPGQSPGRL EALGGRLGRR KGSGPKKERR RTESINSAFA ELRECIPNVP ADTKLSKIKT LRLATSYIAY LMDVLAKDAQ SGDPEAFKAE LKKADGGRES KRKRELQQHE GFPPALGPVE KRIKGRTGWP QQVWALELNQ; Positive Samples: SH-SY5Y, A-549, NIH/3T3; Cellular Location: Nucleus, nucleolus, nucleoplasm.

HAND1 belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Specifications

• Antigen: HAND1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HAND1
• Gene Alias: bHLHa27; Class A basic helix-loop-helix protein 27; eHAND; Ehand1; extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1; HAND1; heart and neural crest derivatives expressed 1; heart and neural crest derivatives expressed transcript 1; heart- and neural crest derivatives-expressed protein 1; Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast; Hxt; Th1; Thing1; thing-1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15110, 9421
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.35 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O96004, Q64279
• Gene Symbols: HAND1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 16-215 of human HAND1 (NP_0048121).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov