Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Genscript Corporation Antibody Protein Proteins Proteins 1 MG 1/EA
Supplier: Genscript Corporation Z031421
Proheparin-binding EGF-like growth factor (HB-EGF) also known as DTR DTS and HEGFL is a member of the EGF family of mitogens. It is expressed in macrophages monocytes endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle cells epithelial cells and keratinocytes. Compared to EGF HB-EGF binds to the EGF receptor with a higher affinity and has been shown to bemore mitogenic likely due to its ability to bind to heparin and heparin sulfate proteoglycans. HB-EGF has also been reported to act as a diphtheria toxin receptor mediating endocytosis of the bound toxin. Heparin-binding EGF-like growth factor has been shown to interact with NRD1 Zinc finger and BTB domain-containing protein 16 and BAG1.
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction