HBEGF Monoclonal Antibody (OTI10A4), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-4561	100 μL

Catalog No. 50-168-4561 Supplier OriGene Supplier No. TA812463

Description

Mouse Monoclonal Antibody

HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.

Specifications

• Antigen: HBEGF
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI10A4
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: HBEGF
• Gene Accession No.: Q99075
• Gene Alias: DTR, DTS, DTSF, HEGFL
• Gene Symbols: HBEGF
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 20-208 of human HBEGF produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1839
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1