HBEGF Monoclonal Antibody (OTI10A4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA812463

Catalog No. 50-168-4561

Description

HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.

Specifications

• Antigen: HBEGF
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: HBEGF
• Gene Alias: DTR, DTS, DTSF, HEGFL
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1839
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Clone: OTI10A4
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q99075
• Gene Symbols: HBEGF
• Immunogen: Human recombit protein fragment corresponding to amino acids 20-208 of human HBEGF produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1