Invitrogen™ HCK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144762

Catalog No. FEPA5144762

Description

Immunogen sequence: CMKSKFLQVG GNTFSKTETS ASPHCPVYVP DPTSTIKPGP NSHNSNTPGI REAGSEDIIV VA Antigen sequence identity: Mouse 61%; Rat 60%.

Hematopoietic cell kinase (HCK) is a SRC-related kinase expressed in lymphoid and hematopoietic cells and may play a role in some forms of leukemia. (HCK Alias: DKFZp686D0638). HCK is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.

Specifications

• Antigen: HCK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HCK
• Gene Alias: AI849071; B cell/myeloid kinase; B-cell/myeloid kinase; BMK; HCK; HCK proto-oncogene, Src family tyrosine kinase; Hctk; Hematopoietic cell kinase; hemopoietic cell kinase; hemopoietic cell tyrosine kinase; JTK9; p56Hck; p56-HCK; p56-HCK/p59-HCK; p59Hck; p59-HCK/p60-HCK; p61Hck; tyrosine-protein kinase HCK
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3055
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P08631
• Gene Symbols: HCK
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 24-85. Recombinant protein control fragment (Product #RP-109909).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid