HDAC1 Mouse anti-Human, Mouse, Rat, Clone: 4C4G7, Proteintech

Catalog No.	Quantity
50-173-6522	150 μL

Catalog No. 50-173-6522 Supplier Proteintech Group Inc Supplier No. 660851IG150UL

Description

Mouse Monoclonal Antibody

This antibody is raised against residues near the C terminus of human HDAC1. The calculated molecular weight of HDAC1 is 55 kDa, but modified HDAC1 is about 60-65 kDa.

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK/TORC signaling pathway,being active when dephosphorylated and acts independently of CREB1 ′Ser-133′ phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene,StAR.Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintece at the Schaffer collateral-CA1 synapses.May be required for dendritic growth of developing cortical neurons.

Specifications

• Antigen: HDAC1
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 4C4G7
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: HDAC1
• Gene Accession No.: O09106, Q13547, Q4QQW4
• Gene Alias: GON 10, HD1, HDAC1, histone deacetylase 1, RPD3, RPD3L1
• Gene Symbols: Hdac1
• Host Species: Mouse
• Immunogen: HDAC1 Fusion Protein Ag19128
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 297893, 3065, 433759
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1