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Invitrogen™ HDAC1 Polyclonal Antibody
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Catalog No. PIPA585093
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100 μL
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PIPA585093 100 μL
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Catalog No. PIPA585093 Supplier Invitrogen™ Supplier No. PA585093
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (80%), Bovine (98%). Positive Control: 293T, A431, HeLa, HepG2, U87-MG, SK-N-SH, NIH3T3, Rat-2, E8.5 embryo. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HDAC1
Applications ChIP Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene HDAC1
Gene Accession No. O09106, Q13547, Q4QQW4
Gene Alias DKFZp686H12203; GON-10; HD1; Hdac1; Hdac1-ps; Histone deacetylase 1; histone deacetylase 1-like protein; MommeD5; reduced potassium dependency, yeast homolog-like 1; RP4-811H24.2; RPD3; RPD3L1
Gene Symbols HDAC1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human HDAC1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 297893, 3065, 433759
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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