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Invitrogen™ HDAC3 Monoclonal Antibody (7G6C5)
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Catalog No. PIMA515442
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100 μL
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PIMA515442 100 μL
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Catalog No. PIMA515442 Supplier Invitrogen™ Supplier No. MA515442
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Description

Mouse Monoclonal Antibody

MA5-15442 targets HDAC3 in indirect ELISA, IF, ChIP and WB applications and shows reactivity with Human samples. The MA5-15442 immunogen is purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli. MA5-15442 detects HDAC3 which has a predicted molecular weight of approximately 48.8kDa.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HDAC3
Applications ChIP Assay, ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 7G6C5
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene HDAC3
Gene Accession No. O15379
Gene Alias AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45
Gene Symbols HDAC3
Host Species Mouse
Immunogen Purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8841
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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