Invitrogen™ HDAC3 Monoclonal Antibody (7G6C5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515442

Catalog No. PIMA515442

Description

MA5-15442 targets HDAC3 in indirect ELISA, IF, ChIP and WB applications and shows reactivity with Human samples. The MA5-15442 immunogen is purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli. MA5-15442 detects HDAC3 which has a predicted molecular weight of approximately 48.8kDa.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Specifications

• Antigen: HDAC3
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: O15379
• Gene Symbols: HDAC3
• Immunogen: Purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 8841
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ChIP Assay, ELISA, Western Blot, Immunocytochemistry
• Clone: 7G6C5
• Conjugate: Unconjugated
• Gene: HDAC3
• Gene Alias: AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a