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Invitrogen™ HDAC3 Polyclonal Antibody
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Catalog No. 01676645
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100 μg
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Catalog No. Quantity
01-676-645 100 μg
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Catalog No. 01-676-645 Supplier Invitrogen™ Supplier No. PA141039
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Description

Rabbit Polyclonal Antibody

Suggested positive control: Hela whole cell extract, antigen standard for HDAC3 (transient overexpression lysate). Immunogen sequence has 100% homology with many species.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HDAC3
Applications ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene HDAC3
Gene Accession No. O15379, O88895
Gene Alias AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45
Gene Symbols HDAC3
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 2-17 of human HDAC3.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15183, 8841
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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