HDAC3 Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™

Mouse Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-3738	Active Motif 91200	10 μg
50-199-3737	Active Motif 91199	100 μg

Description

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Specifications

• Antigen: HDAC3
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: O15379
• Gene ID (Entrez): 8841
• Immunogen: This antibody was raised against a peptide within the C-terminal region of human HDAC3.
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: HDAC3

• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
• Gene Alias: AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; Histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45
• Gene Symbols: HDAC3
• Isotype: IgG2a
• Purification Method: Protein A
• Product Type: Antibody