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Invitrogen™ HDAC3 Recombinant Rabbit Monoclonal Antibody (4D4)
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Catalog No. MA560648
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MA560648 100 μL
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Catalog No. MA560648 Supplier Invitrogen™ Supplier No. MA560648
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Rabbit Recombinant Monoclonal Antibody

HDAC3 Recombinant Monoclonal Antibody for Western Blot, IHC (P), ELISA

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
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Specifications

Antigen HDAC3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 4D4
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HDAC3
Gene Accession No. O15379
Gene Alias AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45
Gene Symbols HDAC3
Host Species Rabbit
Immunogen A synthesized peptide derived from human HDAC3.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8841
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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