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Invitrogen™ HDAC4 Polyclonal Antibody
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Catalog No. 01675683
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Catalog No. Quantity
01-675-683 100 μg
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Catalog No. 01-675-683 Supplier Invitrogen™ Supplier No. PA141092
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Description

Rabbit Polyclonal Antibody

Suggested positive control: 3T3 whole cell lysate, antigen standard for HDAC4 (transient overexpression lysate), Jurkat or NIH-3T3, Jurkat whole cell lysate.

Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations to the HDAC4 gene have been found in Brachydactyly-mental retardation syndrome (BDMR).
TRUSTED_SUSTAINABILITY

Specifications

Antigen HDAC4
Applications ChIP Assay, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene HDAC4
Gene Accession No. P56524, Q6NZM9
Gene Alias 4932408F19Rik; AHO3; AI047285; BDMR; DKFZp779K1053; HA6116; HD4; HD7; HD7b; HD9; HDAC; HDAC4; HDAC-4; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDACA; HDAC-A; HDRP; Histone deacetylase 4; histone deacetylase A; KIAA0288; KIAA0744; MITR
Gene Symbols HDAC4
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 194-209 of human HDAC4.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 208727, 9759
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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