Invitrogen™ HDC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558580

Catalog No. PIPA558580

Description

Immunogen sequence: PALTSWPSLL GDMLADAINC LGFTWASSPA CTELEMNVMD WLAKMLGLPE HFLHHHPSSQ GGGVLQSTVS ESTLIALLAA RKNKILEMKT SEPDADESCL NARLVAYASD QAHSSVEK Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 94%.

The biogenic amine histamine is an important modulator of numerous physiologic processes, including neurotransmission, gastric acid secretion, and smooth muscle tone. The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase (HDC; EC 4.1.1.22). This homodimeric enzyme is a pyridoxal phosphate (PLP)-dependent decarboxylase and is highly specific for its histidine substrate.

Specifications

• Antigen: HDC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hdc
• Gene Alias: AW108189; HDC; Hdc-a; Hdc-c; Hdc-e; Hdc-s; histidine decarboxylase; L-histidine decarboxylase; MGC163399
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3067
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P19113
• Gene Symbols: Hdc
• Immunogen: Recombinant protein corresponding to Human HDC. Recombinant protein control fragment (Product #RP-88649).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov