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Hemoglobin A (beta chain) Monoclonal Antibody (14G2.G11.F11), Rockland™
SDP

Catalog No. 501990619
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100 μg
25 μL
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Catalog No. Quantity
50-199-0619 100 μg
50-199-0620 25 μL
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Catalog No. 50-199-0619 Supplier Rockland Immunochemicals Supplier No. 200301GS4
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Description

Mouse Monoclonal Antibody

Store vial at -20°C prior to opening. This product is stable at 4°C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use. Reacts specifically with human HbA beta chain isoform. This antibody does not react with the HbS form, HbF (gamma) form, HbC forms. HbA antibody cross reacts with HbA-2.

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon-gamma-G-gamma-A-delta-beta-3'.

Specifications

Antigen Hemoglobin A (beta chain)
Applications ELISA, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 14G2.G11.F11
Concentration 1.04 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene HBB
Gene Accession No. P68871
Gene Alias beta globin chain; Beta-1-globin; Beta-globin; CD113t-C; HBB; Hemoglobin beta chain; hemoglobin beta chain complex; Hemoglobin beta chain, major-form; Hemoglobin beta-1 chain; Hemoglobin subunit beta; Hemoglobin subunit beta-1; hemoglobin, beta; III beta-1 globin; III beta-2 globin; LVV-hemorphin-7; Spinorphin
Gene Symbols HBB
Host Species Mouse
Immunogen Anti-Hemoglobin A (beta chain) Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb beta-subunit conjugated to KLH.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3043
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a λ
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