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Invitrogen™ Hemoglobin alpha Polyclonal Antibody

Chicken Polyclonal Antibody

Supplier:  Invitrogen™ PA19527

Catalog No. 01-674-410


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Description

Description

PA1-9527 detects Hemoglobin alpha in human samples. PA1-9527 has been successfully used in Western blot and ELISA procedures. By Western blot, PA1-9527 detects a 15 kDa protein representing Hemoglobin alpha. PA1-9527 immunogen is a synthetic peptide based on the human hemoglobin alpha protein.

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Hemoglobin alpha
Polyclonal
Unconjugated
Hba1
alpha 1 globin; alpha globin 1; alpha one globin; alpha-1/2-globin; alpha-2 globin chain; alpha-globin; delta globin; GloA; globin, alpha; haemaglobin alpha 1; Hba; HBA1; HBA2; Hba-a1; Hba-a2; HBAM; Hbat1; HBA-T3; HBH; hemoglobin alpha 1 chain; hemoglobin alpha 1 globin chain; hemoglobin alpha chain; hemoglobin alpha, adult chain 1; hemoglobin alpha, adult chain 2; hemoglobin alpha-1/2 chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin subunit alpha-1/2; hemoglobin, alpha 1; LOC287167
Chicken
IgY Fraction
RUO
3039
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P69905
Hba1
Synthetic peptide mixture based on the human hemoglobin alpha protein.
500 μg
Primary
Human
Antibody
IgY
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