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Invitrogen™ Hemolysin BL A Recombinant Mouse Monoclonal Antibody (15C7)

Catalog No. MA566467
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MA566467 200 μg
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Catalog No. MA566467 Supplier Invitrogen™ Supplier No. MA566467
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Mouse Recombinant Monoclonal Antibody

Hemolysin BL A Recombinant Monoclonal Antibody for ELISA

Hemolysin BL (HBL) is a tripartite toxin produced by Bacillus cereus, consisting of three distinct proteins: B, L1, and L2. These components work synergistically to exhibit hemolytic, cytotoxic, and dermonecrotic activities, contributing to its role as a virulence factor in foodborne diarrheal illnesses. The toxin operates by forming pores in cell membranes, leading to cell lysis and fluid accumulation, as demonstrated in ligated rabbit ileal loop assays. The gene encoding Hemolysin BL is located within the Bacillus cereus genome, and its expression is tightly regulated to ensure effective pathogenicity. Structural studies have provided insights into the assembly of the HBL complex, revealing the intricate interactions between its subunits, which are crucial for its functionality.
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Specifications

Antigen Hemolysin BL A
Applications ELISA
Classification Recombinant Monoclonal
Clone 15C7
Concentration 5.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Host Species Mouse
Immunogen Hemolysin BL A.
Purification Method Protein G
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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