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Invitrogen™ Hepatitis B Virus Core Antigen Monoclonal Antibody (1-5)

Catalog No. 01670341
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01-670-341 100 μg
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Catalog No. 01-670-341 Supplier Invitrogen™ Supplier No. MA17607
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Description

Mouse Monoclonal Antibody

MA1-7607 detects HBcAg from virus samples. MA1-7607 has been successfully used in Western blot, ELISA, immunoprecipitation and immunohistochemistry procedures. The MA1-7607 immunogen is a purified recombinant HBcAg core protein. The epitope corresponds to residues surrounding residue 80. Store at 4°C short term, and -80°C long term.

The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. Hepatitis B virus is spherical in shape with a diameter of 42nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Hepatitis B Virus Core Antigen
Applications ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 1-5
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2
Gene Alias ayw; HBc; HBcAg; HBV; HepB
Host Species Mouse
Immunogen Purified recombinant HBcAg.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage 4°C short term, -80°C long term
Product Type Antibody
Form Liquid
Isotype IgG2b
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