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Invitrogen™ Hepatitis B Virus Surface Ayw/Adw Monoclonal Antibody (HB5)
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Catalog No. 01676020
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100 μg
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Catalog No. Quantity
01-676-020 100 μg
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Catalog No. 01-676-020 Supplier Invitrogen™ Supplier No. MA119264
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Description

Mouse Monoclonal Antibody

This antibody recognizes the following Hepatitis B virus (HBV) subtypes: ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-. Specificity of the antibody HB5 was verified by ELISA on panel of virus subtypes. The antibody HB5 does not cross-block with the antibody HB3 (MA1-19263).

The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. The HBV surface protein antigens (HBsAg) are comprised of three carboxyl co terminal HBs proteins termed large (LHBs), middle (MHBs) and small (SHBs, also called major) protein. LHBs and MHBs also share the highly hydrophobic, repetitive, membrane spanning S domain. In addition, MHBs has a 55 amino acid region called preS2. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Hepatitis B Virus Surface Ayw/Adw
Applications ELISA, Immunocytochemistry
Classification Monoclonal
Clone HB5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene Alias HBsAg; HBV; hepatitis b virus surface antigen; HepB
Host Species Mouse
Immunogen Purified HBsAg from human plasma.
Purification Method Sequential chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG2a
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