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Invitrogen™ HERV-FRD Polyclonal Antibody
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Catalog No. PIPA576129
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100 μL
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PIPA576129 100 μL
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Catalog No. PIPA576129 Supplier Invitrogen™ Supplier No. PA576129
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).[supplied by OMIM].
TRUSTED_SUSTAINABILITY

Specifications

Antigen HERV-FRD
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene ERVFRD-1
Gene Accession No. P60508, Q8BI41
Gene Alias Endogenous retrovirus group FRD member 1; endogenous retrovirus group FRD, member 1; envelope glycoprotein syncytin-A; envelope polyprotein; envFRD; ERVFRD-1; ERVFRDE1; FLJ41944; FLJ90611; GLLL6191; Gm52; HERV-FRD; HERV-FRD provirus ancestral Env polyprotein; HERV-FRD_6p24.1 provirus ancestral Env polyprotein; HERV-W/FRD; MGC87585; SU; Surface protein; Syna; Synb; syncytin 2; syncytin a; Syncytin2; syncytin-2; TM; Transmembrane protein; UNQ6191; UNQ6191/PRO20218
Gene Symbols ERVFRD-1
Host Species Rabbit
Immunogen Recombinant protein of human HERV-FRD.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 239167, 288602, 405754
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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