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  5. Tocris Bioscience™ Hesperadin hydrochloride

Tocris Bioscience™ Hesperadin hydrochloride
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Catalog No. 398810
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Catalog No. Quantity
39-881-0 10 mg
39-885-0 50 mg
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Catalog No. 39-881-0 Supplier Tocris Bioscience™ Supplier No. 3988/10
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Description

Potent Aurora kinase B inhibitor

ATP-competitive inhibitor of Aurora B kinase (IC50 = 250 nM). Prevents chromosome alignment and segregation; also induces polyploidy and prevents histone H3-Ser10 phosphorylation. Overrides the spindle assembly checkpoint and induces mitotic exit in monastrol - and taxol -treated HeLa cells.

Chemical Identifiers

CAS 422513-13-1
Molecular Formula C29H32N4O3S

Specifications

Quantity 10 mg
Formula Weight 553.12
Purity >99%
Molecular Weight (g/mol) 516.66
Chemical Name or Material Hesperadin hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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