HEXA Mouse anti-Human, Clone: 3A4F2, Proteintech

Catalog No.	Quantity
50-173-6424	150 μL

Catalog No. 50-173-6424 Supplier Proteintech Group Inc Supplier No. 603371IG150UL

Description

Mouse Monoclonal Antibody

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

Specifications

• Antigen: HEXA
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 3A4F2
• Concentration: 1.86 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: HEXA
• Gene Accession No.: P06865
• Gene Alias: HEXA, Hexosaminidase subunit A, TSD
• Gene Symbols: HEXA
• Host Species: Mouse
• Immunogen: HEXA Fusion Protein Ag1854
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3073
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b