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Invitrogen™ HFE Polyclonal Antibody
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Catalog No. PIPA588983
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100 μL
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PIPA588983 100 μL
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Catalog No. PIPA588983 Supplier Invitrogen™ Supplier No. PA588983
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SSQMWLQLSQ SLKGWDHMFT VDFWTIMENH NHSKESHTLQ VILGCEMQED NSTEGYWKYG YDGQDHLEFC PDTLDWRAAE PRAWPTKLEW ERHKIRARQN RAYLERDCPA QLQQLLELGR GVLDQQVPPL VKVTHHVTSS VTTLRCRALN YYPQNITMKW LKDKQPMDAK EFEPKDVLPN GDGTYQGWIT LAVPPGEEQR YTCQVEHPGL DQPLIVIWEP SPSGTLV; Positive Samples: Mouse liver, Mouse heart; Cellular Location: Cell membrane, Single-pass type I membrane protein.

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin. It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HFE
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.40 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene HFE
Gene Accession No. P70387, Q30201
Gene Alias hemochromatosis; hereditary hemochromatosis protein; hereditary hemochromatosis protein HLA-H; hereditary hemochromatosis protein homolog; Hfe; HFE 1; HFE1; HH; high Fe; HLA H; HLAH; HLA-H; MGC:150812; MGC10379; MGC103790; MHC class I-like protein HFE; Mr2; MVCD7; RT1-CAFE; TFQTL2
Gene Symbols HFE
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 80-306 of human HFE (NP_0004011).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15216, 3077
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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