HGAL Monoclonal Antibody (1H1-A7), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  LIFE TECHNOLOGIES 14975882

Catalog No. 14-975-882

Description

The MAb 1H1-A7 recognizes human germinal center-associated lymphoma (HGAL) protein. HGAL is expressed in germinal centers, spleen, thymus, and germinal center-derived lymphomas. HGAL is localized to the cytoplasm of cells within the dark zone of the germinal center and functions to enhance the activation of RhoA leading to negative regulation of lymphocyte motility. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL). The 1H1-A7 antibody recognizes the protein product of the M17 gene, the mouse homolog of the HGAL protein.

HGAL Monoclonal antibody specifically detects HGAL in Human, Mouse samples. It is validated for ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Specifications

• Antigen: HGAL
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: Q6RFH4, Q8N6F7
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 1H1-A7
• Conjugate: Unconjugated
• Gene: GCSAM
• Gene Alias: GAL; GCAT2; Gcet; Gcet2; Gcsam; germinal center associated signaling and motility; germinal center associated, signaling and motility; germinal center B-cell-expressed transcript 2 protein; germinal center expressed transcript 2; germinal center-associated lymphoma protein; Germinal center-associated signaling and motility protein; germinal center-associated, signaling and motility; hGAL; human germinal center-associated lymphoma; M17; M17-L; MGC40441
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14525, 257144
• Content And Storage: 4° C
• Form: Liquid