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Invitrogen™ HGF Monoclonal Antibody (SBF5)
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Catalog No. PIMA514160
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500 μL
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Catalog No. Quantity
PIMA514160 500 μL
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Catalog No. PIMA514160 Supplier Invitrogen™ Supplier No. MA514160
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Description

Mouse Monoclonal Antibody

MA5-14160 targets Hepatocyte Growth Factor in WB and ICC/IF applications and shows reactivity with Human and Mouse samples. The MA5-14160 immunogen is recombinant human HGF protein.

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HGF
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone SBF5
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Hgf
Gene Accession No. P14210, Q08048
Gene Alias C230052L06Rik; DFNB39; Fibroblast derived tumor cytotoxic factor; fibroblast-derived tumor cytotoxic factor; F-TCF; hepatocyte growth factor; Hepatocyte growth factor (hepapoietin A; hepatocyte growth factor (hepapoietin A; scatter factor); Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain; Hepatopoeitin A; hepatopoeitin-A; HepatopoietinA; hepatopoietin-A; Hgf; HGF/SF; HGFB; HPTA; Lung fibroblast derived mitogen; lung fibroblast-derived mitogen; NK1; NK2; Scatter factor; scatter factor); SF; SF/HGF
Gene Symbols Hgf
Host Species Mouse
Immunogen Recombinant human HGF protein.
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15234, 3082
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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