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Invitrogen™ HGK Polyclonal Antibody
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Catalog No. PIPA5104232
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100 μL
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PIPA5104232 100 μL
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Catalog No. PIPA5104232 Supplier Invitrogen™ Supplier No. PA5104232
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MAP4K4.

MAP4K4 (HGK) is a serine/threonine kinase which plays an important role in stress-activated MAPK core signaling pathways, the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HGK
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MAP4K4
Gene Accession No. O95819, P97820
Gene Alias 9430080K19Rik; AU043147; AU045934; AW046177; epididymis secretory protein Li 31; FLH21957; FLJ10410; FLJ20373; FLJ90111; HEL-S-31; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; HGK; HPK/GCK-like kinase HGK; KIAA0687; Map4k4; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; mitogen activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; NCK interacting kinase; nck-interacting kinase; NIK; Ste20 group protein kinase HGK
Gene Symbols MAP4K4
Host Species Rabbit
Immunogen A synthesized peptide derived from human MAP4K4(Accession O95819), corresponding to amino acid residues E410-R460.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26921, 301363, 9448
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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