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HIRA Monoclonal Antibody (WC15), Active Motif™
SDP

Mouse Monoclonal Antibody

$156.65 - $620.58

Specifications

Antigen HIRA
Clone WC15
Concentration 1 mg/mL
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-2718
SDP
Encompass
View Documents
Active Motif
39556
10 μg
Each for $156.65
Only null left
Add to Cart
 
50-199-2717
SDP
Encompass
View Documents
Active Motif
39555
100 μg
Each for $620.58
Only null left
Add to Cart
 
Description

Description

HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochromatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
Specifications

Specifications

HIRA
1 mg/mL
Monoclonal
Liquid
RUO
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; Tuple1
HIRA
IgG
Protein G
Antibody
WC15
Immunoprecipitation, Western Blot
Unconjugated
Mouse
Human, Mouse
P54198, Q61666
15260, 7290
This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.
Primary
-20°C, Avoid Freeze/Thaw Cycles
HIRA
Videos
SDS
Documents

Documents

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