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HIRA Monoclonal Antibody (WC15), Active Motif™

Mouse Monoclonal Antibody
$156.65 - $620.58
Specifications
Antigen | HIRA |
---|---|
Clone | WC15 |
Concentration | 1 mg/mL |
Applications | Immunoprecipitation, Western Blot |
Classification | Monoclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-2718
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Active Motif
39556 |
10 μg |
Each for $156.65
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50-199-2717
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Active Motif
39555 |
100 μg |
Each for $620.58
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Description
HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochromatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.Specifications
HIRA | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8 | |
AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; Tuple1 | |
HIRA | |
IgG | |
Protein G | |
Antibody |
WC15 | |
Immunoprecipitation, Western Blot | |
Unconjugated | |
Mouse | |
Human, Mouse | |
P54198, Q61666 | |
15260, 7290 | |
This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA. | |
Primary | |
-20°C, Avoid Freeze/Thaw Cycles | |
HIRA |
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