Cytiva HiScreen™ Capto™ adhere Multimodal Prepacked Column

Description

For intermediate purification and polishing of monoclonal antibodies after the protein A capture step

• Strong multimodal anion exchanger with N-benzyl-n-methyl ethanolamine ligand
• Offers alternative selectivity compared to traditional anion exchangers
• In flowthrough mode, removal of leached protein A, aggregates, host cell proteins, nucleic acids and viruses from MAbs is performed
• Antibodies pass directly through the column while the contaminants remain bound
• Highly cross-linked agarose matrix
• Ready-to-use columns for convenient process development optimization
• Bed height of 10cm is designed to allow method optimization and parameter screening
• Easily connected in series to achieve 20cm bed height

Specifications

• Buffer: 1M Acetic Acid, 1M NaOH
• Product Type: HiScreen Capto adhere column
• Bed Volume: 4.7mL
• Diameter (English) Inner: 0.3 in.
• Diameter (Metric) Inner: 7.7mm
• Quantity: 1 x 4.7mL
• Height (English): 3.93 in.
• Height (Metric): 100mm
• Flow Rate: <600cm/hr.
• Material: Polypropylene
• Ligand Type: N-benzyl-n-methyl Ethanolamine
• Max. Pressure: 3 bar
• pH Range: 3 to 12
• Particle Size: 75μm
• Support Type: Highly Cross-linked Agarose
• Content And Storage: 4° to 30°C
• Column Type: Multimodal Column
• For Use With (Application): Optimization and parameter screening