Invitrogen™ Histone H1.4 Recombinant Rabbit Monoclonal Antibody (22H1L5)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 703551

Catalog No. 70-355-1

Description

This antibody is predicted to react with Monkey, Bovine, Pig. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Histone H1.4
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P10412
• Gene Symbols: H1-4, HIST1H1E
• Immunogen: Peptides corresponding to human H1.4 [1) aa21-aa33 2) aa164-aa176].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ChIP Assay, Immunocytochemistry
• Clone: 22H1L5
• Conjugate: Unconjugated
• Gene: H1-4
• Gene Alias: dJ221C16.5; H1 histone family, member 4; H1 VAR.2; H1.12 linker histone, cluster member; H1.4; H1-12; H14; H1-4; H1d; H1e; H1f4; H1s-4; H1var2; Hist1h1c; Hist1h1d; Hist1h1e; histone 1, H1e; Histone 1d; Histone cluster 1; histone cluster 1, H1d; histone cluster 1, H1e; histone H1.2; histone H1.4; Histone H1b; histone H1e; histone H1s-4; MGC116819
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3008
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov