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Invitrogen™ Histone H3.3B Polyclonal Antibody
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Catalog No. FEPA5144914
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100 μL
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Catalog No. Quantity
FEPA5144914 100 μL
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Catalog No. FEPA5144914 Supplier Invitrogen™ Supplier No. PA5144914
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KPHRYRPGTV ALREIRRYQK STELLIR Antigen sequence identity: Mouse 100%; Rat 100%.

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Histone H3.3B
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene H3-3B
Gene Accession No. P84243
Gene Alias H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3.3A; H3.3b; H3/b; H3-3A; H3-3b; H3F3; H3F3A; H3F3B; Histone 3; Histone H3.3; PP781
Gene Symbols H3-3B
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 38-64. Recombinant protein control fragment (Product #RP-110243).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3021
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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