Histone H3S10ph Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-3972	Active Motif 39254	10 μL
50-199-3971	Active Motif 39253	100 μL

Description

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

• Antigen: Histone H3S10ph
• Applications: ChIP Assay, Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Immunogen: This Histone H3 phospho Ser10 antibody was raised against a peptide including phospho-serine 10 of histone H3.
• Primary or Secondary: Primary
• Product Type: Antibody

• Concentration: Conc. Not Determined
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
• Isotype: IgG
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles