Histone H4 (monomethyl R3) Rabbit, Clone: RM195, Abnova™

Rabbit monoclonal antibody raised against synthetic monomethyl peptide of human Histone H4 (monomethyl R3).

Supplier:  Abnova Corporation MAB12784

Catalog No. 89-947-516

Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq]

Specifications

• Antigen: Histone H4 (monomethyl R3)
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (0.2 ug/mL-1 ug/mL) Western Blot (0.5 ug/mL-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene Alias: H4/p/MGC24116
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 121504
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: RM195
• Description: Rabbit monoclonal antibody raised against synthetic monomethyl peptide of human Histone H4 (monomethyl R3).
• Formulation: In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
• Gene Symbols: HIST4H4
• Immunogen: A synthetic monomethyl peptide corresponding to residues surrounding R3 of Histone H4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts to Histone H4 monomethylated at Arginine 3. No cross reactivity with unmodified Arginine 3, asymmetric or symmetric dimethylated Arginine 3, and citrullinated Arginine 3 in Histone H4.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG