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Histone H4 (monomethyl R3) Rabbit, Clone: RM195, Abnova™

Catalog No. 89947516 Shop All Abnova Corporation Products
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89-947-516 100 μg
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Catalog No. 89-947-516 Supplier Abnova Corporation Supplier No. MAB12784
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Description

Rabbit monoclonal antibody raised against synthetic monomethyl peptide of human Histone H4 (monomethyl R3).

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq]

Specifications

Antigen Histone H4 (monomethyl R3)
Applications ELISA, Western Blot
Classification Monoclonal
Clone RM195
Conjugate Unconjugated
Description Rabbit monoclonal antibody raised against synthetic monomethyl peptide of human Histone H4 (monomethyl R3).
Dilution ELISA (0.2 ug/mL-1 ug/mL) Western Blot (0.5 ug/mL-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Gene Alias H4/p/MGC24116
Gene Symbols HIST4H4
Host Species Rabbit
Immunogen A synthetic monomethyl peptide corresponding to residues surrounding R3 of Histone H4.
Purification Method Protein A purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 121504
Test Specificity This antibody reacts to Histone H4 monomethylated at Arginine 3. No cross reactivity with unmodified Arginine 3, asymmetric or symmetric dimethylated Arginine 3, and citrullinated Arginine 3 in Histone H4.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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