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Cytiva™ HiTrap™ Capto™ Adhere

The HiTrap Capto adhere is prepacked with a strong anion exchange multimodal resin for removing contaminants in post-protein A purification.

Supplier:  Cytiva™ 29400456

Catalog No. 01-183-313

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Capto™ adhere is a strong anion exchanger with multimodal functionality. The multimodal functionality gives a different selectivity compared to traditional anion exchangers. Capto™ adhere is designed for post-protein A purification of monoclonal antibodies. Removal of leached protein A, aggregates, host cell proteins, nucleic acids, and viruses from monoclonal antibodies is performed in flowthrough mode at which the antibodies pass directly through the column while the contaminants are adsorbed. For optimal performance of Capto™ adhere, screening/optimization of loading conditions are required.

  • High capacity and productivity in flowthrough mode
  • Savings in time and operating costs with a two-step chromatographic process
  • Wide operational window of pH and conductivity
  • Prepacked HiTrap™ columns for easy screening and convenient process development


1 mL
7 mm
1 in.
<4 mL/min.
4°C to 30°C, 20% Ethanol
Contaminant Removal in Post Protein A Purification
0.3 in.
1 x 1 mL
25 mm
5 bar
Affinity Column
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