Cytiva HiTrap™ MabSelect SuRe™ PCC Columns

Description

Prepacked with MabSelect SuRe™ PCC Protein A Resin for screening and small-scale mAb purification in continuous bioprocessing using periodic counter-current chromatography (PCC)

• Suited for small scale antibody purifications, as well as optimization of methods and parameters, such as sample load and protein binding conditions
• Alkali-stabilized, protein A-derived ligand gives the resin greater stability than conventional protein A-based resins under the alkaline conditions used in cleaning-in-place (CIP) protocols
• These protein A columns provide fast, reproducible, and easy separations in a convenient format
• Highly concentrated elution pools for operating flexibility and small unit operations
• Allows cost-effective cleaning with 0.1 to 0.5 M NaOH over hundreds of purification cycles
• Efficiently inactivates bacteria, mold, and yeast, with improved product quality as a result
• Columns are optimally utilized when they are connected to liquid chromatography systems such as the ÄKTA systems
• High binding capacity: ∼ 60 mg Human IgG/mL Resin at 2.4 min residence time

Specifications

• Product Type: Chromatography Column
• Bed Volume: 1 mL
• Diameter (Metric) Inner: 7 mm
• Quantity: 5/Pk.
• Height (Metric): 25 mm
• Flow Rate: <4 mL/min
• Max. Pressure: 5 bar (0.5 MPa)
• Content And Storage: Store at 2°C to 8°C, 20% Ethanol
• Capacity: ∼60 mg Human IgG/mL Resin
• Column Type: Affinity Column
• For Use With (Application): Antibody Affinity Chromatography
• Matrix: MabSelect SuRe PCC Protein A Resin