Invitrogen™ HLA-DQ1/DQ3 Monoclonal Antibody (HL-37)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA119143

Catalog No. 01-675-915

Description

This antibody reacts with extracellular polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages). Western Blot: non-reducing conditions.

Reacts with polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated b chain of DQ1), but does not react with HLA-DQ2. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Specifications

• Antigen: HLA-DQ1/DQ3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P01920
• Gene Symbols: HLA-DQB1
• Immunogen: Burkitt's lymphoma cell line Raji.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Pig
• Product Type: Antibody
• Isotype: IgG3

• Applications: Flow Cytometry, Immunoprecipitation, Western Blot
• Clone: HL-37
• Conjugate: Unconjugated
• Gene: HLA-DQB1
• Gene Alias: CELIAC1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-D; HLADQ; HLA-DQ; HLADQ1; HLADQ3; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatibility complex, class II, DQ beta 1; MHC Class 2; MHC class II; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta; MHC HLA-D; MHC II HLA
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3119
• Content And Storage: 4°C, do not freeze
• Form: Liquid

Safety and Handling

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