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Invitrogen™ HMGB2 Polyclonal Antibody
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Catalog No. PIPA578006
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100 μL
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PIPA578006 100 μL
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Catalog No. PIPA578006 Supplier Invitrogen™ Supplier No. PA578006
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Description

Rabbit Polyclonal Antibody

Positive Control: 293T, A431, HeLa, HepG2, human HMGB1-transfected 293T, human HMGB2-transfected 293T Predicted Reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HMGB2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Hmgb2
Gene Accession No. P26583
Gene Alias C80539; high mobility group box 2; high mobility group protein 2; High mobility group protein B2; high-mobility group (nonhistone chromosomal) protein 2; high-mobility group box 2; HMG 2; HMG B2; Hmg2; HMG-2; HMGB2; HMG-B2; HMGB-2
Gene Symbols Hmgb2
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human HMGB2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3148
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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