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  6. Invitrogen™ HMGCR Recombinant Rabbit Monoclonal Antibody (23GB6220), Invitrogen™ 

Invitrogen™ HMGCR Recombinant Rabbit Monoclonal Antibody (23GB6220), Invitrogen™
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Catalog No. MA552998
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MA552998 100 μL
MA552999 20 μL
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Catalog No. MA552998 Supplier Invitrogen™ Supplier No. MA552998
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Description

Rabbit Recombinant Monoclonal Antibody

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) is a key enzyme in the mevalonate pathway, which is critical for the biosynthesis of cholesterol and other isoprenoids. HMGCR catalyzes the conversion of HMG-CoA to mevalonate, a rate-limiting step in the production of cholesterol. Due to its central role in cholesterol synthesis, HMGCR is a primary target for statin drugs, which are used to lower cholesterol levels and reduce the risk of cardiovascular disease.
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Specifications

Antigen HMGCR
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB6220
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HMGCR
Gene Accession No. P04035, P51639, Q01237
Gene Alias 3H3M; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH); 3-hydroxy-3-methylglutaryl-CoA reductase; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase; HMDH; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; HMG-CoAR; HMGCR; hydroxymethylglutaryl-CoA reductase; LDLCQ3; MGC103269; Red
Gene Symbols HMGCR
Host Species Rabbit
Immunogen A synthesized peptide derived from human HMGCR (400-470AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15357, 25675, 3156
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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