Invitrogen™ HNF4A Monoclonal Antibody (K9218)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA1199

Catalog No. MA1199

Description

MA1-199 detects HNF4a in human, mouse and rat samples.

Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor. HNF4a is expressed in the liver, kidney, intestine, and pancreas. Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.

Specifications

• Antigen: HNF4A
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: Physiological saline with 0.1% sodium azide
• Gene Accession No.: P22449, P41235, P49698
• Gene Symbols: HNF4A
• Immunogen: Baculovirus-expressed recombinant human HNF4 alpha (aa 3-49).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: K9218
• Conjugate: Unconjugated
• Gene: HNF4A
• Gene Alias: alpha transcription factor 4; FLJ39654; FRTS4; hepatic nuclear factor 4 alpha; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; hepatocyte nuclear factor 4-alpha; HNF4; Hnf-4; HNF4 alpha; Hnf4a; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; HNF-4-alpha; HNF4-alpha; HNF4alpha10; HNF4alpha10/11/12; HNF4alpha11; HNF4alpha12; MODY; MODY1; NR2A1; NR2A21; Nuclear receptor 2A1; nuclear receptor subfamily 2 group A member 1; TCF; TCF14; TCF-14; Transcription factor 14; transcription factor HNF-4
• Host Species: Mouse
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 15378, 25735, 3172
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 1 month. For long term storage store at -20°C
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov