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Invitrogen™ HNF4A Recombinant Rabbit Monoclonal Antibody (SN72-03)
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Catalog No. PIMA532295
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PIMA532295 100 μL
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Catalog No. PIMA532295 Supplier Invitrogen™ Supplier No. MA532295
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor. HNF4a is expressed in the liver, kidney, intestine, and pancreas. Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HNF4A
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Recombinant Monoclonal
Clone SN72-03
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% Glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene HNF4A
Gene Accession No. P41235, P49698
Gene Alias alpha transcription factor 4; FLJ39654; FRTS4; hepatic nuclear factor 4 alpha; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; hepatocyte nuclear factor 4-alpha; HNF4; Hnf-4; HNF4 alpha; Hnf4a; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; HNF-4-alpha; HNF4-alpha; HNF4alpha10; HNF4alpha10/11/12; HNF4alpha11; HNF4alpha12; MODY; MODY1; NR2A1; NR2A21; Nuclear receptor 2A1; nuclear receptor subfamily 2 group A member 1; TCF; TCF14; TCF-14; Transcription factor 14; transcription factor HNF-4
Gene Symbols HNF4A
Host Species Rabbit
Immunogen Synthetic peptide within Human HNF-4-alpha aa 21-70.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15378, 3172
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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