Invitrogen™ hnRNP C1/C2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575278

Catalog No. PIPA575278

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.

Specifications

• Antigen: hnRNP C1/C2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HNRNPC
• Gene Alias: AL022939; bZ1G18.4; C1; C2; D14Wsu171e; fb57h12; fi16b11; heterogeneous nuclear ribonucleoprotein C; heterogeneous nuclear ribonucleoprotein C (C1/C2); heterogeneous nuclear ribonucleoprotein C1; heterogeneous nuclear ribonucleoprotein C2; heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous nuclear ribonucleoprotein C; heterogeneous ribonucleoprotein C1/C2; HNRNP; hnRNP C; hnRNP C protein C-terminal fragment (158 AA); hnRNP C1 / hnRNP C2; hnRNP C1/C2; hnRNP C2; hnRNP core protein C; HNRNPC; hnrnp-C; hnRNPC1; hnRNPC2; HNRPC; Hnrpc1; Hnrpc2; hypothetical protein LOC406352; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; snoRNA MBI-122; SNRPC; wu:fb57h12; wu:fi16b11; zgc:55701
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 290046, 3183
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: G3V9R8, P07910
• Gene Symbols: HNRNPC
• Immunogen: Synthetic peptide corresponding to amino acids 241-290 of Human hnRNP C1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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