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COX IV Rabbit Recombinant Antibody (81-194), ProSci
SDP

Catalog No. 16844163 Shop All ProSci Products
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16-844-163 100 μg
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Catalog No. 16-844-163 Supplier ProSci LLC Supplier No. 811940100
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Rabbit Monoclonal Antibody

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

Antigen COX IV
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Conjugate Unconjugated
Formulation Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Gene Accession No. P13073
Host Species Rabbit
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1327
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C. Avoid freeze / thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Shipping Condition Dry Ice
Research Category Cancer, Endocrine Metabolism, Mitochondrial markers, Mitochondrial metabolism, Neurodegenerative Diseases, Neuroscience, Oxidative phosphorylation, Signal Transduction
Product Line ProSci
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