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HOXB4 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501733799 Shop All Proteintech Group Inc Products
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50-173-3799 150 μL
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Catalog No. 50-173-3799 Supplier Proteintech Group Inc Supplier No. 222561AP150UL
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Description

Rabbit Polyclonal Antibody

HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.

Specifications

Antigen HOXB4
Applications Western Blot
Classification Polyclonal
Concentration 0.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene HOXB4
Gene Accession No. P17483
Gene Alias homeobox B4, Homeobox protein Hox 2.6, Homeobox protein Hox 2F, Homeobox protein Hox B4, HOX 2.6, HOX2, HOX2F, HOXB4
Gene Symbols HOXB4
Host Species Rabbit
Immunogen HOXB4 Fusion Protein Ag17761
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3214
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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