HOXB4 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 222561AP150UL

Catalog No. 50-173-3799

Description

HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.

Specifications

• Antigen: HOXB4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOXB4
• Gene Alias: homeobox B4, Homeobox protein Hox 2.6, Homeobox protein Hox 2F, Homeobox protein Hox B4, HOX 2.6, HOX2, HOX2F, HOXB4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3214
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.28 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P17483
• Gene Symbols: HOXB4
• Immunogen: HOXB4 Fusion Protein Ag17761
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG