HSD11B1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-6721	Proteintech Group Inc 109281AP150UL	150 μL

Description

HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, HSD11B1 can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: HSD11B1
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P16232, P28845, P50172
• Gene ID (Entrez): 15483, 25116, 3290
• Immunogen: HSD11B1 Fusion Protein Ag1361
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: HSD11B1

• Concentration: 0.24 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: 11 beta HSD1, 11 DH, HDL, HSD11, HSD11B, HSD11B1, HSD11L, SDR26C1
• Gene Symbols: HSD11B1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody