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Invitrogen™ HSP20 Monoclonal Antibody (C1)
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Catalog No. PIMA541600
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20 μL
200 μL
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PIMA541600 200 μL
PIMA543766 20 μL
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Catalog No. PIMA541600 Supplier Invitrogen™ Supplier No. MA541600
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Description

Mouse Monoclonal Antibody

HSP20 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

Heat Shock Protein 20 (HSP20), encoded by the HSPB6 gene, is a member of the small heat shock protein (sHSP) family, prominently involved in cellular stress response and maintenance of cytoskeletal integrity. HSP20 is ubiquitously expressed across various tissues, including cardiac and smooth muscle, where its roles are vital in modulating stress resilience and muscle function. It exerts protective effects against apoptosis and oxidative stress by interacting with cell signaling pathways that enhance cellular survival and protein stabilization. In cardiac muscle, HSP20 is known for its cardioprotective actions during ischemic injury, helping preserve myocardial function by inhibiting hypertrophic signaling pathways and promoting muscle relaxation. Studies highlight its involvement in vasodilation processes, as HSP20 interacts with myosin to regulate smooth muscle contraction and dilatation. Beyond its role in muscle physiology, HSP20 has been investigated for its potential therapeutic applications in cardiovascular diseases and metabolic disorders, where its expression and function could be pivotal in disease modulation and treatment strategies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HSP20
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone C1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene HSPB6
Gene Accession No. P97541
Gene Alias AA387366; cardiac heat shock protein p20; cardiac p20; epididymis luminal protein 55; Gm479; Heat shock 20 kDa-like protein p20; heat shock 20-kDa protein; Heat shock protein; heat shock protein 20kDa; heat shock protein beta-6; heat shock protein family B (small) member 6; heat shock protein family B (small) member B6; heat shock protein, alpha-crystallin-related, B6; HEL55; HSP; HSP20; HSPB6; p20; PPP1R91; protein phosphatase 1, regulatory subunit 91
Gene Symbols HSPB6
Host Species Mouse
Immunogen Recombinant protein Heat Shock Protein Beta 6. The antigen corresponds to amino acid range 1-162 of the target protein.
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192245
Target Species Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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WARNING: Cancer - www.P65Warnings.ca.gov
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