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HSPA4 Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501733319 Shop All Proteintech Group Inc Products
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50-173-3319 150 μL
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Catalog No. 50-173-3319 Supplier Proteintech Group Inc Supplier No. 212061AP150UL
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Description

Rabbit Polyclonal Antibody

This antibody well recognized the endogenous HSPA4 protein in mouse brain/ testis tissues.

The HSP 70 family is composed of four highly conserved proteins: HSP 70, HSC 70, GRP 75 and GRP 78. HSP 70 expression is strongly induced in response to heat stress. HSP 70 and HSC 70 play key roles in the cytosolic endoplasmic reticulum and mitochondrial import machinery and are found in both the cytosol and nucleus of mammalian cells. GRP 78 is localized in the endoplasmic reticulum, where it receives imported secretory proteins and is involved in the folding and translocation of nascent peptide chains. GRP 75 expression is restricted to the mitochondrial matrix and aids in the translocation and folding of nascent polypeptide chains of both nuclear and mitochondrial origin. It has been postulated that members of the HSP 70 family act as force-generating motors, relying on the hydrolysis of ATP for their activity

Specifications

Antigen HSPA4
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene HSPA4
Gene Accession No. O88600, P34932, Q61316
Gene Alias APG 2, APG2, Heat shock 70 kDa protein 4, heat shock 70kDa protein 4, HS24/P52, HSP70.4, hsp70RY, HSPA4, RY
Gene Symbols HSPA4
Host Species Rabbit
Immunogen HSPA4 Fusion Protein Ag15581
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15525, 266759, 3308
Target Species Human, Mouse, Non-human Primate, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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