Invitrogen™ HSPBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570049

Catalog No. PIPA570049

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%.

HspBP1 is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. The ATPase domain of Hsp70 binds HspBP1 and upon binding, inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 (3) and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.

Specifications

• Antigen: HSPBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSPBP1
• Gene Alias: 1500019G21Rik; FES1; Heat shock protein; heat shock protein-binding protein 1; HSP; hsp70 interacting protein; hsp70-binding protein 1; Hsp70-binding protein 2; hsp70-interacting protein; hsp70-interacting protein 1; Hsp70-interacting protein 2; HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1; HSPA (Hsp70) binding protein 1; HSPA binding protein, cytoplasmic cochaperone 1; Hspbp; HSPBP1; HspBP2; LOW QUALITY PROTEIN: hsp70-binding protein 1; MGC128574 protein; PP1845; SPA ) binding protein, cytoplasmic cochaperone 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 246146
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q6IMX7
• Gene Symbols: HSPBP1
• Immunogen: synthetic peptide directed towards the middle region of human HSPBP1 (aa 226-275).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov